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. 2024 Feb 25;115(4):1306–1316. doi: 10.1111/cas.16119

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© 2024 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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The interplay of CD4⁺ T cells and molecular subtypes impacts on OS and chemotherapeutic response in MIBC. (A) Kaplan–Meier analysis of OS in TCGA cohort (left) and the ZSHS cohort (right), stratified by CD4⁺ T cells and molecular subtypes. (B) Kaplan–Meier analysis of OS in patients receiving chemotherapy, performed in TCGA cohort (left) and the ZSHS cohort (right), stratified by CD4⁺ T cells and molecular subtypes. Log‐rank test was conducted for Kaplan–Meier analysis. MIBC, muscle‐invasive bladder cancer; OS, overall survival; ZSHS, Zhongshan Hospital.