Table 5. Changes in blood outcomes presented in included studies.
| First author, publication year |
Blood
|
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|
ω6: ω3 ratio
|
Triglycerides (mg/dL)
|
Total cholesterol (mg/dL)
|
HDL (mg/dL)
|
LDL (mg/dL)
|
Fasting glucose (mg/dL)
|
Homocysteine (µM)
|
CRP (mg/L)
|
NO (nmol NO/ mg protein)
|
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| Baseline | Mean change | Baseline | Mean change | Baseline | Mean change | Baseline | Mean change | Baseline | Mean change | Baseline | Mean change | Baseline | Mean change | Baseline | Mean change | Baseline | Mean change | |
| Bihuniak JD, 2016 [21] | 10.4±1.9 | -1.5#* | 99.8±34.8 | -12.5 #* | 205.5±31.9 | -2.3# | 68.1±13.0 | -4.0#* | 117.6±25.6 | -4.0# | NR | NR | NR | NR | NR | NR | NR | NR |
| Vignini A, 2017 [17] | NR | NR | VitVO 125.2±46.9 | -5.8# | 219.6±34.3 | -15.3# | 58.6±14.1 | +7.1#* | 133.1±33.7 | -5.5# | 82.5±9.0 | -0.8# | NR | NR | NR | NR | 43.8±4.9 | -6.6#* |
| PlaVO 127.2±44.3 | -12.0# | 218.3±33.5 | -12.7# | 57.6±15.3 | +6.8#* | 132.4±32.4 | -3.9# | 83.5±9.0 | -2.0# | 41.9±4.2 | +0.7# | |||||||
| Bajerska J, 2018 [20] | MED NR | NR | 157.4±NR | -33.9* | 235.8±NR | -15.5* | 55.3±NR | -0.1 | 149.7±NR | -9.4 | 98.0±NR | -6.4* | 11.5±NR | +0.7* | NR | NR | NR | NR |
| CED NR | NR | 164.1±NR | -38.8 | 226.4±NR | -11.2 | 53.1±NR | -2.0 | 143.1±NR | -4.9 | 98.1±NR | -5.4 | 10.9±NR | +0.8 | NR | NR | NR | NR | |
| Duś-Żuchowska M, 2018 [18] | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | MED 4.5±4.5 | -1.2* | NR | NR |
| CED 4.5±4.4 | -0.9* | |||||||||||||||||
| Muzsik A, 2019 [19] | MED 2.5±0.7∥ | -0.2 | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR |
| CED 2.4±0.7∥ | +0.01 | |||||||||||||||||
| Lombardo M, 2020 [16] | NR | NR | MEN 108.3±65.2 | -22.9 | 219.6±41.7 | -22.8 | 58.3±12.6 | +6.0 | 143.6±36.2 | -28.2* | 92.7±14.0 | -2.5 | NR | NR | NR | NR | NR | NR |
| REG 92.0±39.0 | +8.2 | 202.9±35.5 | -9.3 | 58.9±16.4 | +2.2 | 130.3±29.4 | -7.7 | 92.4±9.4 | -2.2 | |||||||||
Note: Values are reported as: mean ± standard deviation, unless otherwise specified. NR: Not reported; HDL: High density lipoprotein; LDL: Low density lipoprotein; CRP: C-reactive protein; NO: Nitric oxide level; MED: Mediterranean diet group; CED: Central european diet group; MEN: Menopausal women group; REG: Not menopausal; VitVO: Vitaminized virgin olive oil group; PlaVO: Placebo virgin olive oil group; IG: Intervention group; CG: Control group; ∥: values obtained in red blood cells; #: mean change was computed as the difference in means between baseline and follow-up using data from the publication; *p < 0.05.