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. Author manuscript; available in PMC: 2024 Apr 11.
Published in final edited form as: Cell Rep. 2023 Nov 11;42(11):113421. doi: 10.1016/j.celrep.2023.113421

Figure 6. Chromatin accessibility dynamics during transdifferentiation in cochlear organoids.

Figure 6.

(A–E) Chromatin accessibility at the promoters of the known and predicted key regulator TFs Atoh1 (A), Pou4f3 (B), Tcf4 (C), Sox9 (D), and Atf3 (E).

(F and G) Average accessibility pattern for peaks within clusters 3 (F) and 1 (G) and enrichment of peaks for sequence motifs recognized by key regulator TFs with dynamic expression in the RNA-based gene regulatory network model.