TABLE 5.
Improvements in model performance (C‐index).
| Primary endpoint events | ASCVD events | |||
|---|---|---|---|---|
| C‐index (95% CI) | p value | C‐index (95% CI) | p value | |
| Base model | 0.715 (0.637–0.793) | 0.707 (0.613–0.801) | ||
| Base model + 24‐h SBP a | 0.721 (0.645–0.797) | .521 | 0.711 (0.617–0.805) | .503 |
| Base model + daytime SBP a | 0.716 (0.638–0.794) | .935 | 0.707 (0.614–0.801) | .969 |
| Base model + nighttime SBP a | 0.734 (0.660–0.808) | .036 | 0.731 (0.641–0.821) | .024 |
| Base model + dipping status a | 0.726 (0.646–0.806) | .007 | 0.726 (0.634–0.817) | .004 |
| Base model + 24‐h SBP + dipping status b | 0.728 (0.648–0.808) | .008 | 0.727 (0.637–0.817) | .005 |
| Base model + daytime SBP + dipping status b | 0.728 (0.648–0.807) | .007 | 0.726 (0.635–0.818) | .004 |
| Base model + nighttime SBP + dipping status b | 0.731 (0.653–0.809) | .053 | 0.733 (0.643–0.823) | .054 |
Note: Base model includes age, sex, body mass index, smoking, alcohol use, diabetes, dyslipidemia, HF, history of cardiovascular disease (including MI, and revascularization therapy), types of antihypertensive drugs, eGFR and office SBP.
Abbreviations: ASCVD, atherosclerotic cardiovascular disease; CI, confidence interval; eGFR, estimated glomerular filtration rate; HF, heart failure; MI, myocardial infarction; SBP, systolic blood pressure.
p values are differences of base model versus base model + 24‐h SBP or + daytime SBP or + nighttime SBP or + dipping status.
p values are differences of base model + ambulatory blood pressure monitoring indices versus base model + ambulatory blood pressure monitoring measures + dipping status.