Table 1.
Normal and glaucoma subject characteristics
| SAP parameters | OCT parameters | ||||||
|---|---|---|---|---|---|---|---|
| n Subjects (males) | Mean age ± SD | Median HFA MD |
Median HFA PSD | Median intereye Δ in HFA MD |
Mean sectors/eye < 5th %ile | Most affected RNFL sectorsa | |
| Normal | 24 (10) | 61.9 ± 7.3 | -0.04 | 1.32 | 0.38 | 0.29 | NSN, IIN, TST |
| Glaucoma (all) | 25 (15) | 68.0 ± 9.1 | -4.57 | 5.71 | 3.10 | 3.72 | I, [IIT, SST] |
| Mildb | 10 (6) | 66.6 ± 11.1 | -3.21 | 3.06 | 2.40 | 2.85 | IIT, [SSN, I, SST] |
| Moderateb | 6 (2) | 64.8 ± 6.7 | -6.29 | 9.01 | 2.27 | 3.75 | [I, SST], IIN |
| Severeb | 9 (7) | 71.6 ± 7.7 | -12.8 | 9.36 | 15.37 | 4.67 | [I, IIT], SST |
Abbreviations: SAP standard automated perimetry, OCT optical coherence tomography, SD standard deviation, HFA Humphrey Field Analyzer, MD mean deviation, PSD pattern standard deviation, RNFL retinal nerve fibre layer, SSN superior superonasal, NSN nasal superonasal, IIN inferior inferonasal, I inferior, IIT inferior inferotemporal, TST temporal superotemporal, SST superior superotemporal
aRNFL clock-hour sectors most often below normal limits (in rank order, bracketed sectors have equivalent rankings)
bClassification for each subject based on whichever of their eyes has the lowest HFA MD value; Mild: both eyes MD ≥ -6 dB; Moderate, worst eye MD < -6 dB but ≥ -12 dB; Severe, worst eye MD < -12 dB