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. 2017 Mar 28;113(8):938–949. doi: 10.1093/cvr/cvx052

Figure 2.

Figure 2

Myocardial miR-375 knockdown attenuates post-MI LV dysfunction. (A) Quantitative RT–PCR analysis of miR-375 expression at day 5 and day 28 in the scrambled ctrl or LNA-anti-miR-375 treated hearts (normalized to control group U6; n = 5). ***P < 0.001 vs. sham group; $< 0.05 vs. LNA anti-miR-375 treated group. (B, C) Quantification of %EF and %FS, in the hearts treated with scrambled or LNA anti-miR-375. %EF, percent ejection fraction; %FS, percent fractional shortening. n = 5–7/group. **P< 0.01 vs. scrambled ctrl group.