Table 4.
PFTs and CPET parameter values (mean ± sd) for each participant group. Abbreviations in Table 3.
| Controls | 0 | I | II | III | IV | |
|---|---|---|---|---|---|---|
| FVC (L) | 4.73±1.05 | 3.75±0.76 | 4.54±0.96 | 4.22±1.06 | 3.92±0.78 | 3.86±0.61 |
| FVC% | 114.6±13.11 | 114.5±12.02 | 107.43±13.12 | 103.14±15.47 | 97±11.15 | 79±15.56 |
| FEV1 (L) | 3.84±1.01 | 2.83±0.37 | 3.66±0.74 | 3.34±0.86 | 3.01±0.55 | 2.48±0.56 |
| FEV1% | 110.8±13.15 | 105±14.14 | 105.5±9.3 | 98.95±16.65 | 89.89±10.24 | 61±9.9 |
| FEV1/SVC% | 105.33±7.39 | 104±4.24 | 103.36±5.4 | 102.29±7.09 | 98.67±12.46 | 82±24.04 |
| TLC (L) | 6.21±1.48 | 5.51±0.76 | 6.18±1.29 | 5.58±1.24 | 5.09±0.98 | 5.04±1.1 |
| TLC% | 98.71±9.93 | 105.5±16.26 | 95.86±14.7 | 88.19±14.87 | 80.78±8.89 | 70±14.14 |
| DLCO (ml/mmHg/min) | 25.87±11.82 | 22.03±7.35 | 27.75±5.78 | 27.34±6.29 | 22.79±6.65 | 18.86±5.23 |
| DLCO% | 94±20.61 | 87±15.56 | 93.5±17.26 | 94.1±16.2 | 78.11±19.59 | 57±18.38 |
| VA% | 100.43±12.49 | 92.5±0.71 | 94.14±15.01 | 91.33±14.97 | 84.22±8.24 | 74±14.14 |
| DLCO/VA% | 90.71±13.89 | 93±15.56 | 99.36±12.46 | 103.29±15.12 | 91.67±17.51 | 75.5±10.61 |
| VEpeak(L/min) | 86.92±26.18 | 83.35±27.51 | 80.16±22.17 | 75.9±25.26 | 63.1±15.88 | 68.65±36.98 |
| VTinitial (L) | 0.63±0.22 | 0.82±0.11 | 0.66±0.2 | 0.59±0.15 | 0.7±0.21 | 0.56±0.11 |
| VTpeak (L) | 2.54±0.74 | 1.67±0.79 | 2.18±0.57 | 2.04±0.7 | 1.87±0.47 | 1.54±0.25 |
| VTpeak/VTinitial | 4.09±0.52 | 2.13±1.25 | 3.43±0.79 | 3.45±0.84 | 2.73±0.49 | 2.84±1.02 |
| RR (1/min) | 35.1±8.66 | 51.5±7.78 | 37.86±9 | 37.43±7.54 | 34.11±6.31 | 43±16.97 |
| BR% | 38.43±11.21 | 19.7±11.88 | 36.1±16.45 | 39.49±13.84 | 45.09±10.02 | 30.5±20.51 |
| SAO2, initial (%) | 97±1.05 | 95.5±3.54 | 97.29±1.33 | 96.57±1.16 | 97±1.22 | 96±0 |
| SAO2, peak (%) | 96.3±1.16 | 96.5±3.54 | 96.71±1.9 | 96±2.53 | 95.67±1.87 | 86±4.24 |
| DeSaO2 (%) | -0.7±1.06 | 1±0 | -0.57±1.65 | -0.57±2.36 | -1.33±2.12 | -10±4.24 |
| PetCO2,initial(mmHg) | 38.1±2.33 | 34.5±0.71 | 35.21±4.66 | 35.81±2.73 | 33.78±4.06 | 33.5±3.54 |
| PetCO2, AT (mmHg) | 44.9±5.49 | 40±2.83 | 40.79±4.66 | 41±3.65 | 38.22±5.7 | 40.5±0.71 |
| PetCO2, peak (mmHg) | 38.3±5.93 | 30±7.07 | 36.71±4.07 | 36.38±3.76 | 36±5.05 | 38±11.31 |
| VE/VCO2, intercept | 0.04±2.15 | -3.79±5.85 | 0.98±1.54 | 0.54±2.07 | 1.03±2.09 | 2.58±10.42 |
| VE/VCO2, slope | 25.92±3.16 | 36.34±14.08 | 28.64±4.28 | 29.12±3.8 | 29.92±5.87 | 31.51±13.99 |
| HRR% | 5.99±9.56 | 19.3±4.53 | 8.46±7.58 | 7.91±11.14 | 11.09±12.24 | 10.6±10.47 |
| O2 pulse% | 113.5±19.28 | 117.5±20.51 | 104.93±18.18 | 92.86±18.01 | 92.56±18.77 | 68.5±3.54 |
| DELTA O2 pulse (ml/beat) | 10.7±3.37 | 11.5±6.36 | 10.57±2.77 | 9.29±2.95 | 7.56±1.33 | 7±0 |
| VO2/Wslope (ml/min/watt) | 10.04±1.18 | 9.95±0.86 | 9.47±1.11 | 9.04±1.37 | 8.81±1.21 | 7.91±0.8 |
| HR/VO2 (beat/ml) | 47.57±17.09 | 41.58±22.37 | 46.05±14.33 | 43.7±16.04 | 48.82±8.77 | 54.53±12.91 |
| PASinitial mmHg) | 120.4±14.18 | 122±1.41 | 125.86±20.75 | 121.9±13.35 | 122.89±21.54 | 117.5±3.54 |
| PASpeak (mmHg) | 177.9±22.04 | 164.5±0.71 | 177.43±30.42 | 178.33±22.24 | 169.33±28.96 | 167.5±50.2 |
| PADinitial (mmHg) | 75.4±8.76 | 80±8.49 | 81.43±6.61 | 86.48±9.76 | 83.33±10.51 | 88±9.9 |
| PADpeak (mmHg) | 80.7±10.73 | 76±5.66 | 94±10.9 | 96.1±12.39 | 92.11±18.34 | 92±14.14 |
| RER | 1.18±0.04 | 1.2±0.01 | 1.14±0.07 | 1.18±0.08 | 1.16±0.08 | 1.11±0.11 |
| VO2, peak (ml/kg/min) | 33.51±6.74 | 26.8±11.46 | 28.41±7.93 | 25.9±6.81 | 21.59±5.52 | 19.45±3.46 |
| VO2% | 109±15.37 | 95.5±21.92 | 95.5±15.79 | 85.38±16.54 | 78±14.47 | 60.5±3.54 |
| AT (ml/kg/min) | 19.68±3.12 | 13.9±5.94 | 16.87±4.27 | 15.8±3.75 | 13.38±3.65 | 13.5±0.42 |
| AT% | 64.5±9.44 | 49.5±12.02 | 57.14±8.93 | 52.38±10.51 | 48.33±11.35 | 42.5±6.36 |
| W (watt/min) | 198.7±55.19 | 138.5±88.39 | 177.29±54.96 | 161.24±55.87 | 134.33±34.08 | 162.5±24.75 |
| W% | 118.8±20.93 | 93.5±21.92 | 100.57±17.01 | 92.14±18.42 | 89.67±26.2 | 74±2.83 |