Table 2.
Clinical outcomes baseline and post-3 month washed microbiota transplantation
| Variable |
Responders1
|
Non-responders1
|
||||||
|
n
|
Baseline, mean ± SD
|
3-month post-WMT, mean ± SD
|
P value
|
n
|
Baseline, mean ± SD
|
3-month post-WMT, mean ± SD
|
P value
|
|
| HBI (three-month post-WMT) | 7 | 5.7 ± 0.8 | 2.4 ± 0.5 | 0.014 | 4 | 5.0 ± 0.0 | 7.0 ± 2.3 | 0.157 |
| CDAI (three-month post-WMT) | 7 | 196.5 ± 21.7 | 76.4 ± 29.5 | 0.018 | 4 | 190.0 ± 13.3 | 238.5 ± 50.1 | 0.068 |
| Stool frequency (number/d) | 7 | 1.7 ± 1.0 | 0.6 ± 0.5 | 0.023 | 4 | 1.5 ± 0.6 | 3.5 ± 2.4 | 0.180 |
| Pain (scale 0-3) | 7 | 0.7 ± 0.5 | 0.3 ± 0.5 | 0.083 | 4 | 0.5 ± 0.6 | 0.5 ± 0.6 | 1.000 |
| hs-CRP (mg/L) | 7 | 3.6 ± 6.1 | 2.1 ± 2.0 | 0.500 | 4 | 14.8 ± 15.8 | 29.6 ± 19.0 | 0.144 |
| ESR (mm/h) | 7 | 15.9 ± 17.0 | 10.9 ± 11.2 | 0.340 | 4 | 43.3 ± 31.6 | 54.0 ± 33.0 | 0.273 |
| Fecal calprotectin (ug/g) | 6 | 367.6 ± 159.9 | 374.2 ± 290.4 | 0.753 | 4 | 391.6 ± 120.9 | 561.2 ± 140.2 | 0.144 |
| SES CD score | 4 | 5.3 ± 2.1 | 3.3 ± 2.5 | 0.285 | 4 | 9.3 ± 7.4 | 17.5 ± 7.1 | 0.068 |
1
Values compared by Wilcoxon signed-rank tests.
Clinical outcomes of responders’ baseline and post-washed microbiota transplantation (WMT) and non-responders’ baseline and post-WMT. The data are presented as means ± SD. WMT: Washed microbiota transplantation; HBI: Harvey-Bradshaw index; CDAI: Crohn’s Disease Activity Index; hs-CRP: High-sensitivity C-reactive protein; ESR: Erythrocyte sedimentation rate; SES: Simple Endoscopic Score; CD: Crohn’s disease.