Figure 6.

FOXO1 overexpression promoted radiation-induced apoptosis in NPC cell lines and revered radiation-induced apoptosis in HOXB2-OE NPC cell lines. (A) Flow cytometry was performed to detect the apoptosis rates of NPC cells after transfection. (B) The TUNEL assay showed changes in apoptosis in NPC cell lines after transfection. FOXO1-OE, forkhead box protein O1 overexpression; HOXB2-OE, homeobox 2 overexpression; HOXB2-OE + FOXO1, co-transfection with HOXB2-OE and FOXO1-OE in NPC cell lines; NC, negative control; NPC, nasopharyngeal carcinoma; TUNEL, terminal deoxynucleotidyl transferase dUTP nick-end labeling.