Table 5.
Logistic regression models for treatment type as a predictor of in-hospital death – 2002-2014 Nationwide Inpatient Sample *
| TPE vs. IVIG: † | OR | 95% CI |
|---|---|---|
| OVERALL: | ||
| Model 1 – Unadjusted | 2.78 | 1.99, 3.88 |
| Model 2 – Risk-Adjusted | 2.57 | 1.82, 3.62 |
| Model 3 – Propensity-score adjusted | 2.48 | 1.77, 3.48 |
| Model 4 – Propensity-score matched | 2.91 | 2.03, 4.16 |
| MALE: | ||
| Model 1 – Unadjusted | 2.62 | 1.68, 4.08 |
| Model 2 – Risk-Adjusted | 2.34 | 1.49, 3.66 |
| Model 3 – Propensity-score adjusted | 2.33 | 1.49, 3.64 |
| Model 4 – Propensity-score matched | 2.84 | 1.76, 4.59 |
| FEMALE: | ||
| Model 1 – Unadjusted | 3.02 | 1.82, 5.00 |
| Model 2 – Risk-Adjusted | 2.98 | 1.76, 5.07 |
| Model 3 – Propensity-score adjusted | 2.71 | 1.62, 4.53 |
| Model 4 – Propensity-score matched | 2.99 | 1.69, 5.26 |
| Period 1 (2002-2007): | ||
| Model 1 – Unadjusted | 3.44 | 1.83, 6.44 |
| Model 2 – Risk-Adjusted | 3.08 | 1.60, 5.94 |
| Model 3 – Propensity-score adjusted | 3.07 | 1.64, 5.79 |
| Model 4 – Propensity-score matched | 3.39 | 1.77, 6.48 |
| Period 2 (2008-2014): | ||
| Model 1 – Unadjusted | 2.58 | 1.72, 3.89 |
| Model 2 – Risk-Adjusted | 2.29 | 1.51, 3.47 |
| Model 3 – Propensity-score adjusted | 2.29 | 1.51, 3.48 |
| Model 4 – Propensity-score matched | 2.80 | 1.77, 4.45 |
*
Note 1: No significant interaction by sex or time period in unadjusted, risk-adjusted or propensity-score adjusted models.
†
Note 2: Risk-adjusted models include age group, Charlson comorbidity index and admission status as covariates. Propensity score adjustment or matching was based on a logistic regression model that includes age group, Charlson comorbidity index and admission status as covariates.
Abbreviations: CI=Confidence Interval, IVIG=Intravenous Immunoglobulin, OR=Odds Ratio, TPE = Therapeutic plasma exchange.