Fig. 5.

Evaluation results of AI-PBPK model-predicted time-dependent distribution of nanoparticles (NPs) to tumors. (A) Comparisons between observed and predicted NPs in tumors (%ID/g) for all datasets (i.e., all types of NPs and different tumors) and (B) predicted-to-observed ratio versus model prediction plot. Abbreviations: %2e and %3e, represent the percentage of data points within the 2-fold and 3-fold errors, respectively; Adj-R2 represent the adjusted determination coefficients.