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Effect of tetanus immunization on synonymous (ds) and nonsynonymous (dn) substitution rates. Intrasample ds and dn values for patients 1 through 4. Significant dn/ds ratios away from neutrality, i.e., dn/ds either <1 or >1, are defined as those plots with error bars which have significantly deviated either below or above the x = y line, respectively.
