Table 4.
Time interval and CVD categorya | Number of patients (n = 11 106) | Risk (%) (95% CI)b | aOR (95% CI)c | Bonferroni-corrected P-valued |
---|---|---|---|---|
Coronary artery disease | ||||
13–24 months before surgery | 190 | 1.7 (1.5–2.0) | Reference | – |
1–12 months before surgery | 170 | 1.5 (1.3–1.8) | 0.88 (0.71–1.08) | 0.99 |
0–12 months after surgery | 83 | 0.7 (0.6–0.9) | 0.42 (0.32–0.54) | <0.001 |
13–24 months after surgery | 99 | 0.9 (0.7–1.1) | 0.51 (0.40–0.65) | <0.001 |
Heart failure | ||||
13–24 months before surgery | 138 | 1.2 (1.0–1.5) | Reference | – |
1–12 months before surgery | 104 | 0.9 (0.8–1.1) | 0.75 (0.58–0.97) | 0.14 |
0–12 months after surgery | 52 | 0.5 (0.3–0.6) | 0.37 (0.27–0.51) | <0.001 |
13–24 months after surgery | 60 | 0.5 (0.4–0.7) | 0.42 (0.31–0.57) | <0.001 |
Hypertension | ||||
13–24 months before surgery | 127 | 1.1 (1.0–1.3) | Reference | – |
1–12 months before surgery | 151 | 1.4 (1.2–1.6) | 1.19 (0.94–1.51) | 0.73 |
0–12 months after surgery | 82 | 0.7 (0.6–0.9) | 0.64 (0.49–0.85) | 0.01 |
13–24 months after surgery | 94 | 0.8 (0.7–1.0) | 0.74 (0.57–0.97) | 0.14 |
Dysrhythmia | ||||
13–24 months before surgery | 271 | 2.4 (2.2–2.7) | Reference | – |
1–12 months before surgery | 322 | 2.9 (2.6–3.2) | 1.20 (1.02–1.41) | 0.13 |
0–12 months after surgery | 351 | 3.2 (2.8–3.5) | 1.31 (1.12–1.54) | 0.004 |
13–24 months after surgery | 315 | 2.8 (2.5–3.5) | 1.17 (1.00–1.38) | 0.27 |
Venous thromboembolism | ||||
13–24 months before surgery | 74 | 0.7 (0.5–0.8) | Reference | – |
1–12 months before surgery | 51 | 0.5 (0.3–0.6) | 0.69 (0.48–0.98) | 0.20 |
0–12 months after surgery | 162 | 1.5 (1.2–1.7) | 2.20 (1.67–2.90) | <0.001 |
13–24 months after surgery | 73 | 0.7 (0.5–0.8) | 0.98 (0.71–1.36) | 0.99 |
aOR, adjusted odds ratio; CI, confidence interval; CVD, cardiovascular disease.
Five most common CVD categories were determined according to the number of patients with an emergency department visit or unplanned hospitalization during 13–24 months before bariatric surgery. The other tables include all CVD categories.
Composite of at least one emergency department visit or unplanned hospitalization.
Adjusted odds ratios are for each 12 months of period vs. the reference period (i.e. 13–24 months before the index bariatric surgery), as calculated with conditional logistic regression.
Corrected for comparisons of five categories.