Table 2.
Genotype data for hypoxia loci in seals showing high and low dive performance
| Locus | SNP-ref | Genotype | High P | Low P | Position | MAF-1980s | MAF- ~2010 |
|---|---|---|---|---|---|---|---|
| HIF1A | 96892683 | CC | 16 | 11 | Upstream variant | 0.44 | 0.438 |
| CA | 23 | 21 | |||||
| AA | 7 | 14 | |||||
| 96894173 | CC | 12 | 9 | Upstream variant | 0.45 | 0.5 | |
| CT | 22 | 20 | |||||
| TT | 12 | 17 | |||||
| HIF3A | 45676640 | AA | 38 | 37 | Non-synonymous | 0.147 | 0.052 |
| AG | 7 | 9 | |||||
| GG | 1 | 0 | |||||
| SETX | 30169236 | CC | 42 | 37 | Non-synonymous | 0.118 | 0.052 |
| CT | 4 | 9 | |||||
| TT | 0 | 0 | |||||
| HYOU1 | 30169060 | GG | 28 | 21 | Upstream variant | 0.275 | 0.254 |
| GT | 17 | 21 | |||||
| TT | 1 | 4 | |||||
| MB | 30169078 | CC | 37 | 28 | Upstream variant | 0.225 | 0.149 |
| GC | 7 | 17 | |||||
| GG | 2 | 1 |
Within each locus, the SNP reference and position relative to the locus is shown. Also shown are changes in MAF comparing females born in the 1980s (N = 51) with those born between 2005 and 2015 (N = 57).