TABLE 1.
Summary of results of infectivity assays using BCBL-1-derived KSHV virion preparations
| Cell origin | Cell line or type (description) | ORF29 RT-PCR resultc |
|---|---|---|
| Lymphoid | BL30a (EBV-negative Burkitt’s lymphoma) | − |
| BL41a (EBV-negative Burkitt’s lymphoma) | − | |
| Ramosa (EBV-negative Burkitt’s lymphoma) | − | |
| BJABa (EBV-negative Burkitt’s lymphoma) | − | |
| Louckesa (EBV-negative Burkitt’s lymphoma) | − | |
| Daudia (EBV-positive Burkitt’s lymphoma) | − | |
| BL41B95-8a (EBV-positive Burkitt’s lymphoma) | − | |
| Rajia (EBV-positive Burkitt’s lymphoma) | − | |
| IB4a (EBV positive) | − | |
| Namalwaa (EBV-positive Burkitt’s lymphoma) | − | |
| CEMx174 (B-cell–T-cell hybrid) | − | |
| U937 (monocyte derived) | − | |
| CD19+ B cellsa,b (primary B cells) | + | |
| Endothelial | HUVECa (human vascular endothelial cells [HPV transformed]) | − |
| HMECa (human microvascular endothelial cells [HPV transformed]) | − | |
| AEC (human aortic endothelial cells [HPV transformed]) | − | |
| BB19 (human brain endothelial cells [HPV transformed]) | + | |
| 181GB1-4 (human brain endothelial cell [HPV transformed]) | + | |
| Primary neonatal capillary endothelial cellsa | + | |
| Primary adult capillary endothelial cellsa | − | |
| Mixed primary adult capillary endothelial cellsa | − | |
| Epithelial | HCT-8 (human rectal epithelial [adenocarcinoma]) | − |
| HT29 (colon epithelial [adenocarcinoma]) | − | |
| 343MG (brain epithelial) | − | |
| OMK637 (owl monkey kidney) | + | |
| 293a (human kidney) | + | |
| Fibroblastoid | HUf23 (foreskin fibroblastoid cells) | − |
| Veroa (African green monkey kidney) | − | |
| COS-7 (African green monkey kidney) | − | |
| BHK-21a (baby hamster kidney) | + | |
| Prostate cancer-derived lines | BPH-1a | − |
| ND-1a | − | |
| Ln-Capa | + | |
| Other cancer-derived lines | A549 (human lung carcinoma) | + |
| CHELI (Chediak-Higachi syndrome) | + | |
| FaDu (squamous cell carcinoma, pharynx) | − | |
| RPMI2650 (squamous cell carcinoma, nasal septum) | − | |
| SCC15 (squamous cell carcinoma, tongue) | + |
a
Cells were tested in the absence and presence of TPA to induce lytic growth from a possibly latent stage of infection.
b
Prepared and cultured by the method of Blackbourn et al. (5).
c
+, positive; −, negative.