Table 1. Clinical characteristics of LT patients who underwent TS for lung cancer resection.
Characteristic | Value |
---|---|
Participants | 7 (100.0) |
Sex, male/female | 6 (85.7)/1 (14.3) |
Body mass index, kg/m2 | 23.3 (19.7; 30.3) |
Indication for LT | |
COPD | 3 (42.9) |
SLT/BLT | 1 (33.3)/2 (66.6) |
IPF | 4 (57.1) |
SLT/BLT | 4 (100.0)/0 |
Transplant procedure | |
SLT | 5 (71.4) |
BLT | 2 (28.6) |
Age at LT, years | 56.6 (46.0; 66.0) |
Age at TS, years | 64.0 (54.0; 67.0) |
Time from LT to TS (overall), years | 5.7 (1.5; 9.3) |
Site of TS | |
Native lung | 4 (57.1) |
Transplant lung | 3 (42.9) |
Smoking status prior to LT | |
Never smoker | 1 (14.3) |
Former smoker | 6 (85.7) |
Pack years | 20 (5; 45) |
Immunosuppressive therapy | |
Prednisolone + MMF | |
+ tacrolimus | 4 (57.1) |
+ ciclosporin | 3 (42.9) |
Comorbidities | |
Charlson comorbidity index | 10 (7; 14) |
CLAD prior to TS | 5 (71.4) |
Arterial hypertension | 5 (71.4) |
CAD | 2 (28.6) |
Chronic renal failure | 3 (42.9) |
Hyperlipoproteinemia | 5 (71.4) |
Diabetes mellitus | 3 (42.9) |
Data are shown as number with percentage or median (minimum; maximum). LT, lung transplantation; TS, thoracic surgery following transplantation; COPD, chronic obstructive pulmonary disease; SLT, single LT; BLT, double LT; IPF, idiopathic pulmonary fibrosis; MMF, mycophenolate; CLAD, chronic lung allograft dysfunction; CAD, coronary artery disease.