. Author manuscript; available in PMC: 2024 Apr 12.

Published in final edited form as: J Alzheimers Dis. 2023;96(2):683–693. doi: 10.3233/JAD-230629

Table 1.

Demographic and clinical variables for the participants analyzed for cross-site inter-rater and test-retest reliability/reproducibility assessments

Demographic and clinical variables	Cross-site inter-rater reliability (n = 30)	Test-retest repeatability (n = 18)	Preliminary analysis of construct validity (N = 53)
Age (y, mean ± SD)	75.8 ± 8.1	73.1 ± 1	75 ± 3
Education (y, mean ± SD)	19.7 ± 13.1	17 ± 2	16.4 ± 3.4
Sex (M:F)	17:13	2:1	29:24
Baseline MoCA Score (mean ± SD)	25.8 ± 2.6	25.7 ± 3.4	26 ± 2.7
Total WMH volume (cm³): baseline (mean ± SE)	11.10 ± 6.19	11.43 ± 0.24	15.7 ± 2.44
Total WMH volume (cm³): follow-up	10.85 ± 6.27	11.83 ± 0.19	15.76 ± 2.40
WMH growth volume (cm³)	1.41 ± 0.88	1.43 ± 0.08	1.84 ± 0.37
WMH regression volume (cm³)	1.65 ± 0.93	0.94 ± 0.06	1.79 ± 0.31
WMH Fazekas Score (Follow-up)	2.6 ± 0. 9	2.06 ± 1.10	2.21 ± 0.89

SD, standard deviation; SE, Standard error; MoCA, Montreal Cognitive Assessment; WMH, white matter hyperintensities.