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. Author manuscript; available in PMC: 2024 Apr 12.
Published in final edited form as: Clin Infect Dis. 2020 Dec 17;71(10):e571–e579. doi: 10.1093/cid/ciaa298

Table 4.

Prevalence of Nonvaccination to Hepatitis A Among Risk Groups and Immunization Cohort in the United States, NHANES 2007–2016

2007–2016
2007–2010
2011–2016
Relative % Change (95% CI)a
n/N % (95% CI) n/N % (95% CI) n/N % (95% CI)

Persons with hepatitis B or hepatitis Cb 232/315 75.1 (68.9–81.2) 107/144 78.3 (70.9–85.6) 125/171 63.8 (51.5–76.2) −18.4 (−35.4 to −1.4)*
Men who had any sex with menc 183/289 65.2 (58.4–72.1) 37/062 52.4 (38.1–66.8) 146/227 64.0 (56.2–71.7) 21.9 (−12.2 to 56)
Persons who reported drug used
 Having used, not IDU 1556/2197 71.7 (69.0–74.3) 682/910 75.2 (72.1–78.3) 874/1287 65.2 (61.2–69.2) −13.3 (−19.5 to −71)*
 IDU 276/390 73.1 (672–79.0) 121/163 75.1 (678–82.4) 155/227 674 (58.6–76.1) −10.3 (−24.4 to 3.8)
Immunization birth cohorte 1884/8560 25.9 (24.0–278) 608/2013 34.6 (30.4–38.8) 1276/6547 23.4 (21.2–25.6) −32.4 (−42.4 to −22.4)*

All estimates are weighted except for n/N.

Abbreviations: CI, confidence interval; HAV, hepatitis A virus; IDU, injection drug use; NHANES, National Health and Nutrition Examination Survey; n/N, number of negative anti-HAV results over total number of tested samples.

Prevalence estimates among risk groups were age-adjusted using the US 2000 standard population. Risk groups only included US-born adults aged ≥20 years.

a

Relative percentage changes between 2007–2010 and 2011–2016.

*

P < .05.

b

Those who tested positive for hepatitis B surface antigen or hepatitis C RNA.

c

Males 20–69 years old only. Data are not available in NHANES 2007–2008.

d

Adults 20–69 years old only. Included cocaine, crack cocaine, heroin, or methamphetamine. Excluded marijuana.

e

Those born after 2004 and aged ≥2 years during 2007–2016. Since 2006, the Advisory Community on Immunization Practice (ACIP) recommends all children aged 12–23 months to have hepatitis A routine vaccination.