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. 2021 Jul 7;148(13):1545–1553. doi: 10.1017/S0031182021001128

Table 1.

Effect of treatment during the enteral stage of the infection1 on the host intestinal parasite burden and T. spiralis female fecundity

CBi/L CBi+
Males Females Males Females
Treatment Variable: nAP2
Control 6.5 (2–17)a 2.0 (0–5)a 13.5 (9–19)a 22.0 (10–27)a
ABZ 7.0 (3–8)a 1.5 (0–3)a 13.5 (10–17)a 8.0 (3–17)a
S4A 6.5 (1–8)a 2.0 (0–10)a 19.5 (13–24)a 17.0 (14–20)a
S10A 7.0 (3–14)a 0 (0–3)a 15.0 (5–23)a 21.0 (20–23)a
Variable: Ff3
Control 29 ± 15.2 344 50 ± 25.0 46 ± 16.6
ABZ
S4A
S10A

nAP, total number of intestinal adult parasites; Ff, T. spiralis female fecundity.

nAP differences among treatments within genotype and sex were evaluated with the nonparametric Kruskal–Wallis test followed by Dunn's test for between-groups comparison (nAP).

For each column, differences between groups not sharing the same superscript are significant at the 0.05 level.

1

Mice were treated on days 5, 6 and 7 p-i and sacrificed two days after the administration of the last dose (9 days p-i).

2

Median (range).

3

Mean ± s.e.m.

4

Only one female recovered.