Table 2.
Clinical characteristics of patients with choledochal cysts before surgery and healthy control children at various ages
| Age at surgery and group | Sex (Male/Female, n) |
Weight (kg, M[P25,P75]) |
ALT (U/L, M[P25,P75]) |
AST (U/L, M[P25,P75]) |
aCholestasis (Yes/No, n) |
APRI (M[P25,P75]) |
|
|---|---|---|---|---|---|---|---|
| ≤ 1 Month | CC (n = 15) | 7/8 | 3.60[3.00,3.95] | 12.00[5.00,16.00] | 34.00[21.00,43.00] | 7/8 | 0.30[0.19,0.90] |
| Control (n = 29) | 8/21 | 3.80[3.45,4.35] | 16.00[9.00,12.00] | 31.00[22.00,42.50] | 1/28 | 0.32[0.18,0.45] | |
| p | 0.206 | 0.056 | 0.104 | 0.921 | 0.002 | 0.465 | |
| 1–2 Months | CC (n = 27) | 7/20 | 4.50[4.00,4.80] | 19.00[13.00,26.00] | 31.00[25.00,44.00] | 6/21 | 0.09[0.08,0.13] |
| Control (n = 20) | 4/16 | 4.75[4.03,5.20] | 20.00[16.50,31.75] | 33.50[27.00,49.00] | 0/20 | 0.11[0.06,0.19] | |
| p | 0.900 | 0.156 | 0.093 | 0.539 | 0.031 | 0.863 | |
| 2–3 Months | CC (n = 14) | 2/12 | 5.50[5.23,6.00] | 40.50[27.00,90.75] | 54.50[36.25,121.75] | 3/11 | 0.16[0.09,0.44] |
| Control (n = 19) | 6/13 | 5.90[5.15,6.30] | 26.00[18.00,34.00] | 36.00[27.00,48.00] | 0/19 | 0.11[0.09,0.13] | |
| p | 0.416 | 0.265 | 0.013 | 0.035 | 0.067 | 0.045 | |
| > 3 Months | CC (n = 17) | 1/16 | 7.00[6.35,7.90] | 47.00[39.00,70.00] | 59.00[42.00,87.50] | 3/14 | 0.18[0.14,0.45] |
| Control (n = 17) | 2/15 | 7.10[6.25,7.90] | 31.00[27.00,36.50] | 39.00[30.50,45.00] | 0/17 | 0.13[0.10,0.16] | |
| p | 1.000 | 0.972 | 0.002 | 0.004 | 0.227 | 0.010 | |
a: There were no differences in the incidence of cholestasis among the 4 age groups at surgery (46.7% vs. 22.2% vs. 21.4% vs. 17.6%, p = 0.280)
M indicates the median