Table 4.
Quality analysis of the studies using the QUIN Scale for cross in vitro studies [30].
| The QUIN Scale | Authors | ||
|---|---|---|---|
| Criteria: | Gnanasekaran et al., 2020 [26] | Nieminen et al., 2018 [14] | Sugiyama et al., 2022 [10] |
| Clearly stated aims/objectives | 2 | 2 | 2 |
| Detailed explanation of sample size calculation | 0 | 0 | 1 |
| Detailed explanation of sampling technique | 2 | 2 | 1 |
| Details of comparison group | N/A | N/A | N/A |
| Detailed explanation of methodology | 2 | 2 | 1 |
| Operator details | 1 | 2 | 1 |
| Randomization | 0 | 0 | 0 |
| Method of measurement of outcome | 2 | 2 | 2 |
| Outcome assessor details | 2 | 2 | 2 |
| Blinding | 0 | 0 | 0 |
| Statistical analysis | 2 | 2 | 2 |
| Presentation of results | 2 | 2 | 2 |
Adequately specified (Score = 2); Inadequately specified (Score = 1); Not specified (Score = 0); Not applicable (N/A).