Table 4.
ESR values and other laboratory parameters in blood samples from dogs in the INFECTED, SICK and OTHER DISEASE groups and the statistical comparative evaluation.
| Parameter and Units | Reference Interval |
INFECTED Group | SICK Group | OTHER DISEASE Group | |||
|---|---|---|---|---|---|---|---|
| N | Median (95% CI) Min–Max |
N | Median (95% CI) Min–Max |
N | Median (95% CI) Min–Max |
||
| ESR (mm/h) |
<10 | 57 | 11 (10–11) a *** 2–15 |
43 | 39 (31–51) b ns 11–77 |
65 | 41 (31–44.0) c *** 12–87 |
| Hematocrit % |
37.3–61.7 | 57 | 45.6 (44.7–46.7) a *** 33.2–57.5 |
43 | 34.6 (31.3–37.6) b ns 16.5–49.7 |
65 | 32.9 (29.1–35.4) c *** 9.1–56.6 |
| WBC K/µL |
5.05–16.76 | 57 | 9.29 (8.66–9.84) a ns 3.51–19.7 |
43 | 8.80 (7.14–10.5) b ** 3.56–38.5 |
65 | 12.2 (10.8–15.4) c *** 1.4–177.7 |
| Bands K/µL |
0.0–0.3 | 57 | 0.00 (0.00–0.00) a * 0.00–0.21 |
43 | 0.00 (0.00–0.00) b ** 0.00–1.79 |
65 | 0.07 (0.00–0.14) c *** 0.00–4.84 |
| CRP mg/L |
0–0.15 | 57 | 0.80 (0.56–1.19) a *** 0.04–13.6 |
43 | 7.6 (2.2–11.9) b ns 0.0–33.6 |
65 | 7.6 (4.0–13.5) c *** 0.1–48.0 |
| Fibrinogen mg/dL |
104–342 | 56 | 199 (179–214) a *** 103–425 |
43 | 358 (302–429) b ns 163–865 |
65 | 345 (309–487) c *** 30–794 |
| Iron µg/dL |
70–270 | 56 | 106 (99–121) a *** 59–362 |
43 | 80 (69–90) b *** 13–260 |
64 | 123 (95–148) c ns 6–364 |
| UIBC µg/dL |
156–383 | 55 | 244 (223–267) a * 121–395 |
42 | 214 (191–231) b ns 18–379 |
65 | 220 (147–253) c * 1.0–429 |
| Ferritin ng/mL |
95–287 | 56 | 324 (246–367) a *** 95–792 |
42 | 558 (402–662) b ns 136–3235 |
63 | 474 (365–588) c *** 87–5289 |
| HPT mg/dL |
18–117 | 37 | 93 (55–107) a *** 17–398 |
36 | 187 (122–230) b ** 36–599 |
59 | 284 (219–297) c *** 50–917 |
| Total proteins g/dL |
5.5–7.6 | 57 | 6.71 (6.53–6.99) a *** 5.32–8.42 |
43 | 7.59 (7.26–8.71) b *** 4.5–13.3 |
65 | 6.2 (6.0–6.45) c ** 3.7–10.7 |
| Albumin g/dL |
2.4–3.8 | 57 | 3.01 (2.91–3.11) a *** 2.23–3.59 |
43 | 2.24 (1.97–2.63) b * 1.20–3.69 |
65 | 2.63 (2.54–2.79) c *** 1.20–3.85 |
| A/G NA |
0.6–1.3 | 57 | 0.80 (0.77–0.90) a *** 0.44–1.33 |
43 | 0.41 (0.30–0.50) b *** 0.15–1.03 |
65 | 0.74 (0.65–0.82) c ** 0.24–1.16 |
| SPE gamma % |
5–15 | 56 | 12.6 (11.5–14.3) a *** 8.9–39.9 |
43 | 33.2 (20.1–41.9) b *** 10.3–59.9 |
65 | 13.0 (10.2–13.6) c ns 5.1–58.6 |
| IgG mg/dL |
307–787 | 52 | 658 (546–797) a *** 329–2238 |
40 | 1399 (900–2128) b *** 468–4608 |
59 | 464 (420–556) c *** 126–3030 |
| IgM mg/dL |
64–176 | 49 | 143 (123–176) a ns 69–318 |
39 | 157 (135–204) b *** 54–616 |
57 | 102 (89.6–126.4) c ** 23–648 |
Legend: ESR, erythrocyte sedimentation rate; WBC, total leukocyte count; CRP, C-reactive protein; UIBC, unsaturated iron binding capacity; HPT, haptoglobin; A/G, albumin–globulin ratio; SPE gamma, gamma globulin in serum protein electrophoresis; IgG, immunoglobulin G; IgM, immunoglobulin M; NA, not applicable; N, number of samples tested, and comparison statistically evaluated; CI, confidence interval; Min-Max, minimum and maximum values. Statistics: a, group comparison INFECTED vs. SICK; b, group comparison SICK vs. OTHER DISEASE; c, group comparison INFECTED vs. OTHER DISEASE; ns, not significant; * p < 0.05 and 0.01; ** p < 0.01 and 0.001; *** p < 0.001.