Table 2.
Summary of the MEM results.
| Cohort a | Time b | Interaction | ||||
|---|---|---|---|---|---|---|
| β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | |
| Pain | −0.305 (−1.104–0.493) | .453 | 0.223 (0.161–0.287) | .000 | −0.016 (−0.100–0.068) | .709 |
| Tiredness | −0.211 (−1.001–0.586) | .602 | 0.231 (0.169–0.294) | .000 | −0.038 (−0.123–0.046) | .372 |
| Drowsiness | −0.381 (−1.185–0.424) | .353 | 0.219 (0.156–0.281) | .000 | −0.076 (−0.160–0.008) | .077 |
| Nausea | −0.172 (−0.859–0.516) | .624 | 0.175 (0.119–0.231) | .000 | −0.064 (−0.139–0.012) | .101 |
| Lack of appetite | −0.934 (−1.823–−0.016) | .039 | 0.230 (0.159–0.301) | .000 | 0.046 (−0.050–0.141) | .348 |
| Shortness of breath | −0.379 (−1.174–0.417) | .350 | 0.171 (0.112–0.230) | .000 | −0.002 (−0.081–0.078) | .969 |
| Depression | −0.106 (−0.902–0.688) | .792 | 0.164 (0.111–0.217) | .000 | −0.039 (−0.110–0.031) | .275 |
| Anxiety | −0.831 (−1.641–−0.022) | .044 | 0.086 (0.030–0.141) | .002 | 0.044 (−0.030–0.119) | .246 |
| Wellbeing | −0.107 (−0.888–0.675) | .789 | 0.231 (0.170–0.291) | .000 | −0.043 (−0.125–0.039) | .308 |
a The model employs the MAID cohort as a reference, and β represents the parameter estimate (i.e., estimated difference in average numeric rating scale) for the non-MAID cohort relative to the MAID cohort. Negative values of β indicate lower scores in the non-MAID cohort compared to the MAID cohort. b The model treats time as a continuous variable. Positive values of the β parameter suggest that the symptom in question escalated as time approached the provision of MAID. Note: Not all patients completed questionnaires at each time point. Details regarding the missing data are available upon request.