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. 2024 Mar 29;14(7):738. doi: 10.3390/diagnostics14070738

Table 3.

The findings of the ROC analysis with sensitivity, specificity, positive–negative predictive and positive likelihood ratio values demonstrating the success of the Prognostic Nutrition Index (PNI) and albumin in amputation prediction.

Prognostic Nutritional Index (PNI) Albumin
AUC (95% CI) 0.937 (0.911–0.963) 0.938 (0.912–0.964)
p values <0.001 <0.001
Cut off ≤39.005 ≤38.5
Sensitivity (95% CI) 82.7% (74.1–89) 81.8% (73.1–88.3)
Specificity (95% CI) 93.1% (89.3–95.7) 93.1% (89.3–95.7)
PPV (95% CI) 82.7% (74.1–89) 82.6% (73.9–88.9)
NPV (95% CI) 93.1% (89.3–95.7) 92.8% (88.9–95.4)
LR+ (95% CI) 12 (7.7–18.7) 11.9 (7.6–18.5)

ROC: Receiver Operating Characteristic, PPV: positive predictive value, NPV: negative predictive value, AUC: Area under curve, CI: Confidence interval, LR+: Positive likelihood ratio.