ATTRv |
hereditary transthyretin amyloid |
ATTRwt |
wildtype transthyretin amyloid |
AL |
immunoglobulin light chain amyloid |
APOLLO |
phase 3 study of Patisiran for treatment of hereditary transthyretin amyloidosis with polyneuropathy |
CADT |
compound autonomic dysfunction test |
CM |
cardiomyopathy |
ELISA |
enzyme-linked immunosorbent assay |
EMG |
electromyography |
ESC |
electrochemical skin conductance |
FAP |
familial amyloidotic polyneuropathy |
HELIOS |
phase 3 open-label study of Vutrisiran in patients with hereditary transthyretin amyloidosis with polyneuropathy |
IENFD |
intra-epidermal nerve fiber density |
mNIS + 7 |
modified neuropathy impairment score + 7 |
MRC |
medical research council |
NCS |
nerve conduction studies |
NfL |
neurofilament light chain |
NIS |
neuropathy impairment score |
NIS-LL |
neuropathy impairment score lower limb |
NIS-UL |
neuropathy impairment score upper limb |
Norfolk QOL-DN |
Norfolk quality of life diabetic neuropathy |
NT-proBNP |
N-terminal pro-brain-type natriuretic peptide |
OLE |
open-label extension |
PND |
polyneuropathy disability |
PNP |
polyneuropathy |
QST |
quantitative sensory testing |
R-ODS |
Rasch-built overall disability score |
ROC |
receiver operating characteristics |
SFN-SIQ |
small fiber neuropathy-symptom inventory questionnaire |
Simoa |
single-molecule array |
TTR |
transthyretin |
TTRv |
transthyretin gene variant |