Skip to main content
. 2024 Mar 28;25(7):3770. doi: 10.3390/ijms25073770
ATTRv hereditary transthyretin amyloid
ATTRwt wildtype transthyretin amyloid
AL immunoglobulin light chain amyloid
APOLLO phase 3 study of Patisiran for treatment of hereditary transthyretin amyloidosis with polyneuropathy
CADT compound autonomic dysfunction test
CM cardiomyopathy
ELISA enzyme-linked immunosorbent assay
EMG electromyography
ESC electrochemical skin conductance
FAP familial amyloidotic polyneuropathy
HELIOS phase 3 open-label study of Vutrisiran in patients with hereditary transthyretin amyloidosis with polyneuropathy
IENFD intra-epidermal nerve fiber density
mNIS + 7 modified neuropathy impairment score + 7
MRC medical research council
NCS nerve conduction studies
NfL neurofilament light chain
NIS neuropathy impairment score
NIS-LL neuropathy impairment score lower limb
NIS-UL neuropathy impairment score upper limb
Norfolk QOL-DN Norfolk quality of life diabetic neuropathy
NT-proBNP N-terminal pro-brain-type natriuretic peptide
OLE open-label extension
PND polyneuropathy disability
PNP polyneuropathy
QST quantitative sensory testing
R-ODS Rasch-built overall disability score
ROC receiver operating characteristics
SFN-SIQ small fiber neuropathy-symptom inventory questionnaire
Simoa single-molecule array
TTR transthyretin
TTRv transthyretin gene variant