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. 2024 Mar 26;25(7):3687. doi: 10.3390/ijms25073687

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Histologic assessment of perineural scar tissue formation. (A) Connective tissue ratio. The GA group had the highest ratio, which was significantly different from those of the Sham and the GA + FG groups. (B–D) Representative cross sections of the sciatic nerve. (B) The GA + FG group showed limited scar tissue formation (black arrows) adherent to the nerve after 12 weeks. (C) The GA group showed the most extensive epi- and perineural scar tissue formation (black arrows). (D) The Sham group showed the lowest scar tissue formation in terms of both epi- and perineurium (black arrows).