Table 3.

Anti-inflammatory agents under clinical trials for different NDs.

Agent	Phase	Status	Sponsor	Conditions	CT.gov ID
Canakinumab	Phase 2	Active, not recruiting	Novartis Pharmaceuticals	Mild cognitive impairment or mild AD	NCT04795466
Celecoxib	Not applicable	Completed	University of California, Los Angeles	AD, dementia	NCT00065169
Rofecoxib and Naproxen	Phase 2 Phase 3	Completed	National Institute on Aging (NIA)	AD	NCT00004845
Indomethacin	Phase 3	Completed	Radboud University Medical Center	AD	NCT00432081
Prednisone	Phase 3	Completed	National Institute on Aging (NIA)	AD	NCT00000178
Lovostatin, Ibuprofen	Phase 4	Completed	National Institute of Mental Health (NIMH)	AD	NCT00046358
Rifaximin	Phase 1 Phase 2	Unknown	Taipei Medical University Shuang Ho Hospital	PD	NCT03958708
Ciprofloxacin/Celecoxib	Phase 2	Completed	NeuroSense Therapeutics Ltd.	ALS	NCT04165850
Anakinra	Phase 2	Unknown	Charite University, Berlin, Germany	ALS	NCT01277315