Figure 3.

Schematic representation of proteins and biological processes affected by CL alterations within mitochondria. Abbreviations: AAC, ADP/ATP carrier; I, III, IV, complex I, III, IV (respectively); MUC, mitochondrial Ca²⁺ uniporter; MICU1, mitochondrial calcium uptake 1; OPA1, OXPHOS, oxidative phosphorylation; PARL, presenilin-associated rhomboid-like protein; DRP1; dynamin-related protein 1; OPA1, optic atrophy 1; LC3, microtubule-associated protein 1A/1B-light chain 3; Cyt c, cytochrome c; MIC10, mitochondrial contact site and cristae organizing system 10.