Table 2.
Quantitative variables in subjects classified by genotypes of the FTO rs9939609 variant.
| Variables | TT (n = 95) |
AT (n = 42) |
AA (n = 32) |
p Value |
|---|---|---|---|---|
| Sex (M/W), % | 20/80 | 28.6/71.4 | 3.1/96.9 | 0.175 |
| Age (years) | 35.80 (33.48–38.12) | 35.11 (31.60–38.63) | 33.35 (28.48–38.22) | 0.616 |
| Clinical | ||||
| SBP (mm Hg) | 114.38 (111.5–117.2) | 114.19 (109.8–118.5) | 119.12 (112.8–125.4) | 0.376 |
| DBP (mm Hg) | 72.86 (69.7–75.9) | 72.86 (69.7–75.9) | 75.08 (70.5–79.6) | 0.487 |
| Anthropometrical | ||||
| Weight (kg) | 64.08 (59.4–68.7) | 68.3 (61.6–75) | 75.5 (64–86.9) | 0.151 |
| BMI (kg/m2) | 28.02 (25.9–30.1) | 26.91 (23.7–30) a | 35.46 (31–39.8) a | 0.005 |
| Body Fat (%) | ||||
| M (n = 35) | 19.59 (15.6–23.5) | 23.21 (18.6–27.7) | 24.12 | 0.610 |
| W (n = 134) | 29.87 (27.3–32.3) | 29.62 (25.8–33.4) | 32.98 (27.6–38.2) | 0.540 |
| WC (cm) | ||||
| M (n = 35) | 93.87 (83.4–104.2) | 94.91 (81.8–108) | 144.35 | 0.104 |
| W (n = 134) | 88.21 (82.9–93.5) | 85.45 (77–93.8) a | 101.07 (90.9–111.1) a | 0.047 |
| Biochemical | ||||
| TC (mg/dL) | 178.17 (171.1–185.1) | 184.08 (173.5–194.5) | 176.44 (161–191.3) | 0.596 |
| LDL-c(mg/dL) | 107.62 (101.7–113.4) | 112.49 (103.5–121.4) | 110.73 (98.4–123) | 0.647 |
| HDL-c(mg/dL) | ||||
| M (n = 35) | 40.03 (35.1–44.8) | 45.08 (38.9–51.1) | 30.39 | 0.246 |
| W (n = 134) | 45.51 (42.3–48.7) | 47.99 (42.9–53) | 41.97 (35.8–48) | 0.328 |
| TG (mg/dL) | 127.39 (113–141.7) | 122.09 (100.6–143.5) | 125.23 (94.6–155.7) | 0.920 |
| TG/HDL-c ratio | 3.28 (2.8–3.7) | 2.98 (2.2–3.7) | 3.63 (2.6–4.6) | 0.574 |
| TC/HDL-c ratio | 4.31 (4–4.5) | 4.12 (3.7–4.5) | 4.69 (4.09–5.3) | 0.318 |
Data reported in estimated mean and confidence intervals, adjusted by the variables age and sex. The p-value was obtained using the univariate general linear model. SBP: Systolic blood pressure, DBP: Diastolic blood pressure, M: Men, W: Women, TC: Total serum cholesterol, LDL-c: Low-density lipoprotein cholesterol, HDL-c: high-density lipoprotein cholesterol. TG: triglycerides. a Differences between groups.