Table 1.

Major renal diseases highlighting the role of CD-68-positive macrophages in human and animal studies with significant prognostic association [3,4].

Number	Renal Disease	Renal Compartment Semi-Quantitively Assessed for CD-68 Positive Macrophages
1	IgA nephropathy [4]	Endocapillary hypercellularity [4]
2	Systemic lupus erythematosus nephritis [4]	Endocapillary hypercellularity and tubulo-interstitial inflammation [4]
3	Crescentic glomerulonephritis * [3,4]	Extra-capillary macrophage infiltration [3,4]
4	Tubulo-interstitial toxicity * [3]	Tubulo-interstitial macrophage infiltration [3]

* CD-68 has been studied in experimental crescentic glomerulonephritis and tubulointerstitial nephrotoxic animal models as well as in few human studies.