Table 4.

Effects of AVL-3288 on the P50 auditory evoked response to repeated stimuli as change from baseline

Non-smokers		S1 response ms	S1 response mmv	S2 response mmv	P50 Ratio S2/S1
3 mg	mean	−8.83	0.30	0.41	0.02
	sd	10.30	2.55	1.02	0.32
10 mg	mean	0.50	0.30	0.00	−0.25
	sd	2.26	1.07	1.92	0.79
30 mg	mean	0.83	−0.17	−0.32	−0.18
	sd	6.62	1.01	0.60	0.20
Placebo	mean	1.67	0.01	0.42	0.10
	sd	2.34	1.06	1.33	0.39
Smokers
3 mg	mean	−3.17	−0.50	−0.19	0.02
	sd	8.28	0.54	0.68	0.42
Placebo	mean	1.50	−0.40	−0.79	−0.23
	sd	0.71	0.76	0.65	0.11