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. 2024 Apr 5;25(7):4049. doi: 10.3390/ijms25074049

Figure 6.

Figure 6

Effects of lfTSLP and TSLP fragments generated by tryptase and chymase on mediator release from human lung macrophages (HLMs). (A) Effects of lfTSLP (30 ng/mL) (red bar) and of increasing concentrations of the two TSLP fragments generated by tryptase (TSLP1-97 and TSLP98-132) (blue bars) and (B) of the two fragments generated by chymase (TSLP1-36 and TSLP37-132) (blue bars) on VEGF-A release from HLMs. The results show the mean ± SD of eight independent experiments performed with highly purified (≥99%) HLMs from different donors. ** p < 0.01 compared to control (CTR).