Subcellular localisation of B7-H3 in breast cancer-BrM tumours. (a) Chi-square analysis of proportions of BC and BrM cases stratified by B7-H3 subcellular localisation. (b) Chi-square analysis of proportions of matched BC and BrM cases for B7-H3 subcellular localisation compared across breast cancer subtypes (ER+, HER2+, TNBC). (c) KM analysis of B7-H3 subcellular localisation and BCSS in BC. (d) KM analysis of B7-H3 subcellular localisation and BrMSS in BrM tumours. BC, breast cancer; BCSS, breast cancer specific survival; BrMSS, brain metastasis specific survival; ER+, oestrogen receptor; HER2+, human epidermal growth factor receptor 2; KM, Kaplan–Meier; TNBC, triple negative breast cancer.