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. 2024 Apr 5;13(7):2116. doi: 10.3390/jcm13072116

Table 5.

Summary of advanced treatments for post-inflammatory hyperpigmentation in SoC based on recent studies.

Author Study Type Year Laser Therapy Parameters Fitzpatrick Scale No. of Cases Clinical Outcome Adverse Events
Bae et al. [52] Retrospective photographic analysis 2020 Non-ablative fractional 1927 nm laser Low energy, low-density parameters (fluence 5 mJ, spot size 140 μm, depth 170  μm, 5% coverage) IV–VI 61 A mean improvement of 43.24% was assessed by two independent dermatologists, and there was a statistically significant correlation between the raters. No side effects reported.
Li et al. [50] Prospective interventional study 2018 Intense pulsed light Wavelength 560–615 nm, 2–6 treatments over 3–5 weeks III–IV 35 IPL significantly lessened PIH as per physician assessment with an 82.9% satisfaction rate No post-treatment complications
Kasai et al. [45] Retrospective case series 2017 Fractionated 755 nm Alexandrite ps-laser 8 mm spot, fluence 0.4 J/cm2, 750-ps, 10 Hz, 3 sessions at 1- or 2-month intervals III 1 At the 3-year follow-up, the PIH lesions had a 50–75% improvement Deepening of local skin lesions