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. 2024 Apr 2;13(7):2054. doi: 10.3390/jcm13072054

Figure 2.

Figure 2

Multifactorial mechanisms lead to pulmonary hypertension in sarcoidosis and may include hypoxic vasoconstriction, pulmonary vascular rarefaction, parenchymal destruction, left heart disease with postcapillary PH, portal hypertension from liver disease, pulmonary vascular remodeling, changes resembling pulmonary veno-occlusive disease and extrinsic vascular compression due to fibrosing mediastinitis or enlarged lymph nodes.