Figure 1.

Response of target lesions in treatment-naïve and pretreated patients. Best response to mobocertinib. Waterfall plot of maximum change in tumor size on imaging measured according to RECIST v1.1 in all target lesions between baseline and follow-up in pretreated and treatment-naïve patients. Both growth (+20%) and shrinkage (−30%) of tumors are indicated by the dashed lines. One patient experienced a tumor growth of 400%. For better illustration purposes, the Y-axis only shows 100%. Patients with no shrinkage or growth are shown with −1%. Eighteen patients are not shown because there was no measurable disease or because they had no adequate response for assessment. Four patients are not shown because retrospective measurement of lesions was not possible.