Table 1.
Effect of exosomes derived from human umbilical cord mesenchymal stem cells (HucMSC-Exos), hydrolyzed collagen oligopeptides (HCOPs), and HucMSC-Exos + HCOPs on reactive oxygen species (ROS) expression and senescence-associated β-galactosidase (SA-β-Gal) activity in senescent human skin fibroblasts (HSFs).
| Groups | ROS | SA-β-Gal | ||
|---|---|---|---|---|
| Fluorescence Intensity | Percentage of Control % | Positive Rate of SA-β-Gal | Percentage of Control % | |
| Control | 50.9 ± 6.0 a | 100.0 ± 11.7 a | 1.14 ± 0.15 a | 100.0 ± 13.3 a |
| Exos | 22.7 ± 2.5 b | 44.6 ± 5.0 b | 0.69 ± 0.08 b | 60.3 ± 7.0 b |
| HCOPs | 24.1 ± 2.0 b | 47.3 ± 3.9 b | 0.72 ± 0.11 b | 62.8 ± 10.0 b |
| Exos + HCOPs | 12.7 ± 0.7 c | 24.9 ± 1.4 c | 0.34 ± 0.04 c | 30.1 ± 3.7 c |
The data shown are expressed as the mean ± SD from three replicates. Different lowercase letters on bars indicate significant differences among samples (p < 0.05).