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Mechanism of apoptosis in OA (Abbreviations: Bid, BH3-interacting domain death agonist; Bax, Bcl-2-associated X protein; Bcl-2, B cell lymphoma-2; cyt c, cytochrome c; dATP, deoxyadenosine triphosphate; Smac, second mitochondrial-derived activators of caspases; IAPs, Inhibitors of Apoptosis Proteins; Apaf-1, Apoptotic Protease Activating Factor-1).
