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[Preprint]. 2024 Apr 1:2024.03.31.587467. [Version 1] doi: 10.1101/2024.03.31.587467

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Figure 10. — (A) CD40L surface expression in TCR Tregs, CAR Tregs, and CAT Tregs 18h post-activation. Representative histograms on the left and summary data on the right. (B) TIGIT surface expression in TCR Tregs, CAR Tregs, and CAT Tregs 18h post-activation. Representative histograms on the left and summary data on the right. (C) Relative frequency of TIGIT⁻CD40L^low, TIGIT⁺CD40L^low, TIGIT⁻CD40L^hi, and TIGIT⁺CD4L^hi cells among TCR Tregs, CAR Tregs, and CAT Tregs 18h post-activation. (D) Frequency of IFNG producing cells among TIGIT⁻CD40L^low, TIGIT⁺CD40L^low, TIGIT⁻CD40L^hi, and TIGIT⁺CD4L^hi subpopulations for TCR Tregs, CAR Tregs, and CAT Tregs 18h post-activation. For Figures 10A, B, and D, values represent technical replicates of representative experiments. Bars represent mean ± SD. One-way ANOVA test with Tukey’s multiple comparison correction. ****, p < 0.0001; ***, p < 0.001; **, p < 0.01; *, p < 0.05; ns, not significant.