Table 4. Neonatal Facial Coding System (NFCS) and Neonatal Infant Pain Scale (NIPS) scores prior to (Tpre), during (T0) and two (T2) and five (T5) minutes after the painful stimulus, and Premature Infant Pain Profile (PIPP) score on the first, third and seventh days of life.
| 1st day of life | 3rd day of life | 7th day of life | |
|---|---|---|---|
| NFCS | |||
| Tpre | 0.4 ± 1.3 | 0.3 ± 1.0 | Zero |
| T0 | 3.6 ± 4.0 | 2.5 ± 3.0 | 3.0 ± 3.7 |
| T2 | 1.5 ± 2.7 | 0.7 ± 2.1 | 1.7 ± 3.2 |
| T5 | 0.5 ± 1.3 | zero | 0.2 ± 0.6 |
| NIPS | |||
| Tpre | 0.3 ± 1.3 | 0.1 ± 0.3 | Zero |
| T0 | 1.9 ± 1.5 | 1.1 ± 1.5 | 1.7 ± 1.3 |
| T2 | 1.0 ± 1.6 | 0.4 ± 1.3 | 0.8 ± 1.6 |
| T5 | 0.2 ± 0.8 | zero | 0.2 ± 0.6 |
| PIPP | 1.1 ± 1.8 | 1.2 ± 1.5 | 1.3 ± 1.5 |
Repeated-measurement analysis of variance (RM-ANOVA): 1st day = 3rd day = 7th day (NFCS p = 0.40; NIPS p = 0.32; PIPP p = 0.56).