Table 4.
Comparison of clinical features of right-sided and left-sided colon cancer
| Variable | Stage I |
Stage II |
Stage III |
Stage IV |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Left-sided colon cancer (n = 8,816） | Right-sided colon cancer (n = 9,668) | P-value | Left-sided colon cancer (n = 11,130) | Right-sided colon cancer (n = 14,545) | P-value | Left-sided colon cancer (n = 14,549) | Right-sided colon cancer (n = 14,305) | P-value | Left-sided colon cancer (n = 7,196) | Right-sided colon cancer (n = 7,146) | P-value | |
| Female, n (%) | 3,994 (45.3) | 5,024 (52.0) | <0.001 | 4,932 (44.3) | 7,457 (51.3) | <0.001 | 6,572 (45.2) | 7,526 (52.6) | <0.001 | 3,210 (44.6) | 3,613 (50.6) | <0.001 |
| Age, years, median (IQR) | 62 (53–70) | 69 (60–76) | <0.001 | 63 (54–72) | 68 (59–77) | <0.001 | 60 (51–69) | 66 (57–75) | <0.001 | 59 (50–68) | 64 (55–73) | <0.001 |
| Histology, n (%) | <0.001 | <0.001 | <0.001 | <0.001 | ||||||||
| Adenocarcinoma | 8,610 (97.7) | 9,087 (94.0) | 10,414 (93.6) | 12,659 (87.0) | 13,601 (93.5) | 12,408 (86.7) | 6,641 (92.3) | 6,138 (85.9) | ||||
| Mucinous adenocarcinoma | 194 (2.2) | 556 (5.8) | 688 (6.1) | 1,789 (12.3) | 809 (5.6) | 1,587 (11.1) | 457 (6.4) | 812 (11.4) | ||||
| Signet-ring cell adenocarcinoma | 12 (0.1) | 25 (0.3) | 28 (0.3) | 97 (0.7) | 139 (1.0) | 310 (2.2) | 98 (1.4) | 196 (2.7) | ||||
| Chemotherapy, n (%) | <0.001 | <0.001 | <0.001 | <0.001 | ||||||||
| No/unknown | 8,648 (98.1) | 9,595 (99.2) | 7,956 (71.5) | 12,186 (83.8) | 3,674 (25.3) | 4,317 (30.2) | 1,547 (21.5) | 1,914 (26.8) | ||||
| Yes | 168 (1.9) | 73 (0.8) | 3,174 (28.5) | 2,359 (16.2) | 10,875 (74.7) | 9,988 (69.8) | 5,649 (78.5) | 5,232 (73.2) | ||||
| Size, median (IQR) | 2.00 (1.00–3.50) | 2.50 (1.40–4.00) | <0.001 | 5.00 (3.50–6.50) | 5.00 (3.60–7.00) | <0.001 | 4.30 (3.00–5.70) | 4.90 (3.50–6.50) | <0.001 | 5.00 (4.00–6.50) | 5.30 (4.00–7.00) | <0.001 |
| Gradea, n (%) | <0.001 | <0.001 | <0.001 | <0.001 | ||||||||
| High/moderate | 7,885 (93.6) | 8,598 (91.4) | 9,847 (90.1) | 11,679 (81.5) | 11,776 (82.2) | 9,645 (68.4) | 5,120 (76.3) | 4,280 (63.7) | ||||
| Poor/anaplastic | 535 (6.4) | 814 (8.6) | 1,088 (9.9) | 2,648 (18.5) | 2,555 (17.8) | 4,458 (31.6) | 1,586 (23.7) | 2,436 (36.3) | ||||
| T stage, n (%) | <0.001 | <0.001 | <0.001 | <0.001 | ||||||||
| T1 | 4,749 (53.9) | 4,315 (44.6) | 674 (4.6) | 424 (3.0) | 404 (5.6) | 326 (4.6) | ||||||
| T2 | 4,067 (46.1) | 5,353 (55.4) | 1,413 (9.7) | 1,141 (8.0) | 176 (2.4) | 161 (2.3) | ||||||
| T3 | 9,068 (81.5) | 12,362 (85.0) | 9,405 (64.6) | 9,105 (63.6) | 3,634 (50.5) | 3,317 (46.4) | ||||||
| T4 | 2,062 (18.5) | 2,183 (15.0) | 3,057 (21.0) | 3,635 (25.4) | 2,982 (41.4) | 3,342 (46.8) | ||||||
| N stage, n (%) | <0.001 | <0.001 | ||||||||||
| N0 | 8,816 (100.0) | 9,668 (100.0) | 11,130 (100.0) | 14,545 (100.0) | 1,625 (22.6) | 1,142 (16.0) | ||||||
| N1 | 9,780 (67.2) | 9,246 (64.6) | 2,836 (39.4) | 2,458 (34.4) | ||||||||
| N2 | 4,769 (32.8) | 5,059 (35.4) | 2,735 (38.0) | 3,546 (49.6) | ||||||||
IQR = interquartile range.
a
Due to the missing data, the total is 84,950.