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. 2024 Mar 15;25(4):1752–1772. doi: 10.1038/s44319-024-00097-7

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the data associated with this article, unless otherwise stated in a credit line to the data, but does not extend to the graphical or creative elements of illustrations, charts, or figures. This waiver removes legal barriers to the re-use and mining of research data. According to standard scholarly practice, it is recommended to provide appropriate citation and attribution whenever technically possible.

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Figure EV3 — (A) Amount of unique fragments detected per cell from control (n = 95) and STZ oocytes (n = 85. (B) Fragment size distribution from control (n = 95) and STZ oocytes (n = 85 (C) TSS enrichment profile from control (n = 95) and STZ oocytes (n = 85). (D) UMAP depicting scATAC profiles from control (n = 95) and STZ oocytes (n = 85). (E) Volcano plot displaying no differentially accessible regions between control (n = 85) and STZ (n = 95) oocytes. TSS, Transcription starting site; UMAP, Uniform Manifold Approximation and Projection; STZ, Streptozotocin. Data information: Data depicted is biological replicates. For boxplots in panel (A), the lower and upper hinges of the box depict the 1st and 3rd quartiles, and the middle line depicts the median. The upper and lower whiskers extend to the largest or smallest value no further than 1.5 times the interquartile range (1.5*IQR) from the hinge. Data beyond the end of the whiskers are plotted as a violin plot, which are then the minimum and/or maximum values depicted.