Table 1.

Clinical characteristics of study population.

	Patients N = 22 (%)
Age at first tumour diagnosis, years
Median (IQR)	51 (47–65)
<70	4 (18)
≥70	18 (82)
Sex
Male	10 (45)
Female	12 (55)
ECOG PS at baseline
0	13 (59)
≥1	9 (41)
Stage at diagnosis
I-II-II	11 (50)
IV	11 (50)
Synchronous vs metachronous metastases
Sync (<6 months)	11 (50)
Meta (≥6 months)	11 (50)
Primary tumour location
Right	3 (14)
Left	9 (41)
Extraperitoneal rectum	10 (45)
Primary tumour resection
Yes	17 (77)
No	5 (23)
Liver metastases at any time
Yes	11 (50)
No	11 (50)
Lung metastases at any time
Yes	17 (77)
No	5 (23)
Lines of treatments received in total
≤3	15 (68)
>3	7 (32)
Age at brain metastases resection, years
Median (IQR)	58 (48–68)
<70	17 (77)
≥70	5 (23)
ECOG PS at the time of brain metastases resection
0	8 (36)
≥1	14 (64)
Brain metastases presentation
Synchronous	7 (32)
Metachronous	15 (68)
Tumour burden at the time of brain surgery
Intracranial-only disease	8 (36)
Intra and extracranial disease	14 (64)
Number of brain metastases at the time of brain surgery
1	19 (86)
>1	3 (14)