Table 2.
Associations between intravaginal practices and rate of sexually transmitted infection/bacterial vaginosis among women in the Ring Study in southwestern Uganda
Sexually transmitted infection/condition | Overall | Intravaginal practices | ||||
Yes | No | |||||
Rate/100 PYR (95% CI) | Rate/100 PYR (95% CI) | Rate/100 PYR (95% CI) | P value* | uRR (95% CI) | aRR (95% CI) | |
Single-event-per-participant analysis | ||||||
HIV | 5.8 (3.0 to 11.1) | 7.0 (2.9 to 17.0) | 4.7 (1.8 to 12.4) | 0.278 | 1.51 (0.39 to 5.81) | 1.29 (0.29 to 5.67 |
Trichomonas vaginalis | 92.7 (78.7 to 109.0) | 97.4 (76.9 to 123.3) | 88.7 (70.9 to 111.1) | 0.288 | 1.10 (0.79 to 1.52) | 1.10 (0.67 to 1.63) |
Neisseria gonorrhoea | 23.4 (18.3 to 29.9) | 22.8 (15.9 to 32.9) | 23.8 (17.0 to 33.4) | 0.435 | 0.96 (0.58 to 1.57) | 0.99 (0.56 to 1.79) |
Chlamydia trachomatis | 28.4 (22.7 to 35.6) | 27.9 (20.2 to 38.8) | 28.9 (21.2 to 39.4) | 0.446 | 0.97 (0.62 to 1.52) | 0.83 (0.50 to 1.38) |
Bacterial vaginosis | 14.1 (10.6 to 18.6) | 13.4 (8.9 to 20.4) | 14.7 (10.1 to 21.4) | 0.383 | 92 (0.52 to 1.61) | 1.13 (0.53 to 2.37) |
Multiple-events-per-participant analysis | ||||||
T. vaginalis | 88.9 (79.6 to 99.5) | 90.2 (76.8 to 106.0) | 87.9 (75.3 to 102.5) | 0.406 | 1.03 (0.77 to 1.37) | 1.07 (0.80 to 1.43) |
N. gonorrhoea | 28.4 (23.3 to 34.6) | 28.7 (21.5 to 38.1) | 28.2 (21.5 to 37.0) | 0.935 | 1.02 (0.61 to 1.69) | 0.99 (0.59 to 1.67) |
C. trachomatis | 43.6 (37.2 to 51.1) | 36.6 (28.4 to 47.1) | 49.9 (40.7 to 61.2) | 0.030 | 0.73 (0.45 to 1.20) | 0.64 (0.38 to 1.05) |
Bacterial vaginosis | 18.8 (11.1 to 31.7) | 12.1 (4.5 to 32.2) | 24.1 (13.0 to 44.8) | 0.124 | 0.51 (0.13 to 1.95) | 0.48 (0.16 to 1.47) |
Adjusted for age, trial arm, STI/BV at baseline.
*Unadjusted p value comparing the rate of each STI between IVP use and none use.
aRR, adjusted rate ratio; BV, bacterial vaginosis; IVP, intravaginal practice; PYR, person-years at risk.STI, sexually transmitted infection; uRR, unadjusted rate ratio;