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. 2024 Apr 8;14(4):e079497. doi: 10.1136/bmjopen-2023-079497

Table 2.

Associations between intravaginal practices and rate of sexually transmitted infection/bacterial vaginosis among women in the Ring Study in southwestern Uganda

Sexually transmitted infection/condition Overall Intravaginal practices
Yes No
Rate/100 PYR (95% CI) Rate/100 PYR (95% CI) Rate/100 PYR (95% CI) P value* uRR (95% CI) aRR (95% CI)
Single-event-per-participant analysis
 HIV 5.8 (3.0 to 11.1) 7.0 (2.9 to 17.0) 4.7 (1.8 to 12.4) 0.278 1.51 (0.39 to 5.81) 1.29 (0.29 to 5.67
Trichomonas vaginalis 92.7 (78.7 to 109.0) 97.4 (76.9 to 123.3) 88.7 (70.9 to 111.1) 0.288 1.10 (0.79 to 1.52) 1.10 (0.67 to 1.63)
Neisseria gonorrhoea 23.4 (18.3 to 29.9) 22.8 (15.9 to 32.9) 23.8 (17.0 to 33.4) 0.435 0.96 (0.58 to 1.57) 0.99 (0.56 to 1.79)
Chlamydia trachomatis 28.4 (22.7 to 35.6) 27.9 (20.2 to 38.8) 28.9 (21.2 to 39.4) 0.446 0.97 (0.62 to 1.52) 0.83 (0.50 to 1.38)
 Bacterial vaginosis 14.1 (10.6 to 18.6) 13.4 (8.9 to 20.4) 14.7 (10.1 to 21.4) 0.383 92 (0.52 to 1.61) 1.13 (0.53 to 2.37)
Multiple-events-per-participant analysis
T. vaginalis 88.9 (79.6 to 99.5) 90.2 (76.8 to 106.0) 87.9 (75.3 to 102.5) 0.406 1.03 (0.77 to 1.37) 1.07 (0.80 to 1.43)
N. gonorrhoea 28.4 (23.3 to 34.6) 28.7 (21.5 to 38.1) 28.2 (21.5 to 37.0) 0.935 1.02 (0.61 to 1.69) 0.99 (0.59 to 1.67)
C. trachomatis 43.6 (37.2 to 51.1) 36.6 (28.4 to 47.1) 49.9 (40.7 to 61.2) 0.030 0.73 (0.45 to 1.20) 0.64 (0.38 to 1.05)
 Bacterial vaginosis 18.8 (11.1 to 31.7) 12.1 (4.5 to 32.2) 24.1 (13.0 to 44.8) 0.124 0.51 (0.13 to 1.95) 0.48 (0.16 to 1.47)

Adjusted for age, trial arm, STI/BV at baseline.

*Unadjusted p value comparing the rate of each STI between IVP use and none use.

aRR, adjusted rate ratio; BV, bacterial vaginosis; IVP, intravaginal practice; PYR, person-years at risk.STI, sexually transmitted infection; uRR, unadjusted rate ratio;