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. 2024 Mar 29;13:e51298. doi: 10.2196/51298

Table 2.

Description of the variables that will be extracted from raw electrophysiological signals monitored with the medical device NeXus-10 MKII.

Group of variables Electrophysiological signal Physiological variables Description
HRVa or PRVb ECGc or PPGd HRe,f (bpm)g Mean HR
HRV or PRV ECG or PPG IBIf (ms)h Mean IBI
HRV or PRV ECG or PPG pNN50f (%) Percentage of adjacent normal beats intervals differing from each other by >50 ms
HRV or PRV ECG or PPG SDNNf (ms) SD of normal beats intervals
HRV or PRV ECG or PPG RMSSDf (ms) Root mean square of successive differences between normal beats
HRV or PRV ECG or PPG SDSDf (ms) SD of differences between adjacent R-R peaks intervals
HRV or PRV ECG or PPG VLFi (s−2) Absolute power of the VLF band (0.003-0.04 Hz)
HRV or PRV ECG or PPG LFf,j (s−2) Absolute power of the LF band (0.04-0.15 Hz)
HRV or PRV ECG or PPG HFf (s−2)k Absolute power of the HF band (0.15-0.4 Hz)
HRV or PRV ECG or PPG LF/HF ratiof Ratio of LF to HF power
HRV or PRV ECG or PPG HFnf (nu) Relative power of the HF band normalized
PATl ECG and PPG PAT (ms) Mean PAT, the time between the beat detected by ECG and the pulse by PPG
PAT ECG and PPG stdPAT (ms) SD of PAT
Breathing Respiration RRm (Hz) Mean RR
Breathing Respiration Pk (%) Peak of respiratory power spectra
EDAn EDA Tonicf (µS) Average value of the tonic component, that is, slowly changing skin conductance level, also known as SCLo
EDA EDA Phasicf (µS) Average value of the phasic component, that is, fast-changing responses typically associated with short-term events, also known as SCRp
EDA EDA aucPhasicf (µS·s) Area under the curve of the phasic component, which is related to SCR
EDA EDA EDASympf (µS) Electrodermal response in the power spectrum (0.045-0.25 Hz)
Peripheral temperature STq TFingerf (°C) Mean finger temperature
Peripheral temperature ST TGradientf (°C) Mean gradient of finger temperature
Peripheral temperature ST TPowerf (°C2) Mean power of finger temperature

aHRV: heart rate variability.

bPRV: pulse rate variability.

cECG: electrocardiogram.

dPPG: photoplethysmography.

eHR: heart rate.

fThese will also be extracted from the recordings of the Empatica E4 wearable device.

gbpm: beats per minute.

hIBI: interbeat interval.

iVLF: very low frequency

jLF: low frequency.

kHF: high frequency.

lPAT: pulse arrival time.

mRR: respiratory rate.

nEDA: electrodermal activity.

oSCL: skin conductance level.

pSCR: skin conductance response.

qST: skin temperature.