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. 2024 Apr 13;23:102. doi: 10.1186/s12944-024-02089-x

Table 2.

Association of NHHR with kidney stone and a recurrence of passing kidney stones

Exposure Model 1 Model 2 Model 3
OR(95%CI), P-value OR(95%CI), P-value OR(95%CI), P-value
Nephrolithiasis
NHHR 1.08 (1.05, 1.12) < 0.0001 1.07 (1.04, 1.11) < 0.0001 1.04 (1.00, 1.08) 0.0373
Categories
Q1 1.0 1.0 1.0
Q2 1.27 (1.10, 1.46) 0.0012 1.22 (1.05, 1.41) 0.0074 1.15 (0.97, 1.37) 0.1132
Q3 1.47 (1.28, 1.69) < 0.0001 1.40 (1.22, 1.62) < 0.0001 1.25 (1.05, 1.49) 0.0104
Q4 1.55 (1.35, 1.78) < 0.0001 1.47 (1.27, 1.69) < 0.0001 1.28 (1.07, 1.52) 0.0058
P for trend 1.14 (1.10, 1.19) < 0.0001 1.13 (1.08, 1.18) < 0.0001 1.08 (1.02, 1.14) 0.0086
Nephrolithiasis recurrence
NHHR 1.14 (1.10, 1.19) < 0.01 1.12 (1.07, 1.17) < 0.01 1.09 (1.03, 1.14) < 0.01
Categories
Q1 1.0 1.0 1.0
Q2 1.54 (1.19, 1.98) 0.0009 1.46 (1.13, 1.89) 0.0037 1.26 (0.93, 1.70) 0.1380
Q3 1.77 (1.38, 2.27) < 0.0001 1.63 (1.27, 2.09) 0.0001 1.34 (1.00, 1.81) 0.0527
Q4 2.13 (1.68, 2.71) < 0.0001 1.90 (1.49, 2.44) < 0.0001 1.58 (1.18, 2.12) 0.0024
P for trend 1.24 (1.16, 1.33) < 0.0001 1.20 (1.12, 1.29) < 0.0001 1.15 (1.05, 1.25) 0.0026

In the analysis, NHHR was transformed from a continuous variable into a categorical variable using quartiles

OR, odds ratio; 95% CI, 95% confidence interval

Model 1 did not incorporate any variable adjustments

Model 2 adjusted for sex, age, and race

Model 3 extended these adjustments to include a more comprehensive set of variables: sex, age, race, educational level, marital status, Poverty Income Ratio (PIR), Body Mass Index (BMI), vigorous activity, moderate activity, hypertension, diabetes, alcohol and smoking habits