TABLE 1.

Hydrolysis of flavonoid glycosides by human saliva^1,2

Flavonoid glycoside	Aglycone formation
	% of added glycoside
Spiraeoside (quercetin 4′-glucoside)	85.6 ± 1.3
Phloridzin (phloretin 2′-glucoside)	67.8 ± 2.9
Genistin (genistein 7-glucoside)	44.3 ± 4.3
Isoquercetin (quercetin 3-glucoside)	40.5 ± 6.6
Rutin (quercetin 3-rhamnoglucoside)	9.0 ± 0.6
Quercitrin (quercetin 3-rhamnoside)	0
Naringin (naringenin 7-rhamnoglucoside)	0

¹Values are means ± SEM, n = 3–4.

²Saliva from 1 volunteer was incubated for 2 h at 37°C with 25 μmol/L flavonoid glycosides and analyzed by HPLC for the aglycone products and the parent flavonoid glycosides.