Table 1.
Patient demographics
| Study | Kuroki et al. [14] | Cochet et al. [13] | Nakatani et al. [15] | Blockhause et al. [17] | Reddy et al. [12] | Maurhofer et al. [16] | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PFA | Thermal | PFA | Thermal | PFA | Thermal | PFA | Thermal | PFA | Thermal | PFA | Thermal | |
| Patients (n) | 37 | 43 | 18 | 23 | 18 | 23 | 23 | 20 | 305 | 302 | 40 | 160 |
| Male (n (%)) | 28 (76) | 31 (72) | 15 (83) | 17 (74) | 15 (83) | 17 (74) | 15 (65) | 16 (80) | 202 (66) | 195 (65) | 30 (75) | 121 (76) |
| Age (yr) | 59 ± 10 | 62 ± 0 | 58 ± 9 | 59 ± 9 | 56 ± 9 | 60 ± 8 | 57 ± 10 | 59 ± 9 | 62 ± 9 | 63 ± 9 | 62 ± 9 | 12 (8) |
| BMI | NR | NR | NR | NR | 26 ± 4 | 26 ± 3 | 28 ± 4 | 26 ± 4 | 28 ± 5 | 29 ± 5 | 26 ± 4 | 26 ± 4 |
| Persistent AF (n (%)) | 0 (0) | 0 (0) | NR | NR | NR | NR | 11 (48) | 10 (50) | 0 (0) | 0 (0) | 40 (100) | 160 (100) |
| CHA2DS2VASc | NR | NR | NR | NR | 0.5 ± 0.8 | 0.6 ± 0.8 | 1.5 ± 1.1 | 1.7 ± 1.4 | 1.7 ± 1.2 | 1.7 ± 1.2 | NR | NR |
| Congestive heart failure | NR | NR | NR | NR | 0 (0) | 1 (4) | 3 (13) | 5 (25) | 59 (19) | 59 (20) | NR | NR |
| Hypertension | 23 (62) | 20 (47) | 4 (22) | 4 (17) | 4 (22) | 4 (17) | 15 (65) | 8 (40) | 174 (57) | 159 (53) | 26 (65) | 98 (61) |
| Diabetes mellitus | 4 (11) | 2 (5) | 1 (6) | 0 (0) | 1 (6) | 0 (0) | NR | NR | 33 (11) | 32 (11) | 3 (8) | 17 (11) |
| Stroke or TIA | 2 (5) | 3 (7) | 2 (11) | 1 (4) | 1 (6) | 1 (4) | 0 (0) | 2 (10) | 12 (4) | 15 (5) | 2 (5) | 4 (5) |
| CAD/vascular disease | 0 (0) | 6 (14) | 1 (6) | 2 (9) | 1 (6) | 2 (9) | 2 (9) | 5 (25) | 32 (11) | 51 (17) | 8 (20) | 24 (15) |
| Dyslipidemia | NR | NR | 3 (17) | 4 (17) | NR | NR | NR | NR | 133 (44) | 141 (47) | NR | NR |
| Ejection fraction (%) | 63 ± 3 | 60 ± 6 | 62 ± 6 | 61 ± 8 | 62 ± 6 | 61 ± 8 | 56 ± 8 | 55 ± 8 | NR* | NR* | 58 ± 4 | 59 ± 5 |
| Left atrial diameter (mm) | 41 ± 4 | 38 ± 7 | NR | NR | NR | NR | 41 ± 3 | 41 ± 3 | 39 ± 6 | 40 ± 6 | 42 ± 6 | 41 ± 6 |
| AAD (n (%)) | NR | NR | 14 (78) | 17 (74) | 13 (72) | 18 (78) | NR | NR | 185 (61) | 173 (57) | NR | NR |
| Prior AF ablation (n (%)) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | NR | NR | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
Abbreviations: AAD, anti-arrhythmic drug; AF, atrial fibrillation; BMI, body mass index; CAD, coronary artery disease; TIA, transient ischemic attack
*Mean left-ventricular ejection fraction was 60% across both arms