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. Author manuscript; available in PMC: 2024 Apr 14.
Published in final edited form as: J Invest Dermatol. 2003 Jan;120(1):116–122. doi: 10.1046/j.1523-1747.2003.12012.x

Figure 3. Anti-IL-12 antibodies increase TNFα production from UVB-irradiated cells.

Figure 3

(a) Anti-IL-12 antibodies increase TNFα release from UVB-irradiated adult keratinocytes. Adult keratinocytes were irradiated with 30 mJ per cm2 of UVB, 5 J per cm2 of UVA, or sham irradiated, and then given media without (minus symbols) or with (plus symbols) 10 µg anti-IL-12 antibody per ml followed by 24 h of incubation at 37°C. Displayed are TNFα concentrations in the conditioned media. (b) Anti-IL-12 antibodies increase TNFα release from UVB-irradiated fibroblasts. Fibroblasts were irradiated with 30 mJ per cm2 of UVB, or sham irradiated, and then given media without (minus symbols) or with (plus symbols) 10 ng IL-1α per ml, 10 µg anti-IL-12 antibody per ml followed by 24 h of incubation at 37°C. Displayed are TNFα concentrations in the conditioned media.