TABLE 1.

Profile of bioactive compounds in Mentha piperita L. hydroethanolic extract analyzed by LC–MS/MS.

Identified compounds		RT (min)	LOD/LOQ (μg/L)f	Ug	Content (mg/g lyophilized extract)
Organic acids	Fumaric aid	03.90	135.7/167.9	0.0091	01.82 ± 0.02
Phenolic acids	Quinic acid	03.00	25.7/33.3	0.0372	21.03 ± 0.78
	Gallic acid	04.40	13.2/17.0	0.0112	00.15 ± 0.02
	Protocatechuic acid	06.80	21.9/38.6	0.0350	00.92 ± 0.03
	Gentisic acid	08.30	18.5/28.2	0.0167	00.05 ± 0.00
	Chlorogenic acid	08.40	13.1/17.6	0.0213	01.50 ± 0.03
	Caffeic acid	12.10	7.7/9.5	0.0152	01.63 ± 0.03
	p‐Coumaric acid	17.80	25.9/34.9	0.0194	00.41 ± 0.08
	Salicylic acid	21.80	6.0/8.3	0.0158	00.10 ± 0.02
	Rosmarinic acid	26.60	16.2/21.2	0.0130	339.88 ± 04.42
Flavones	Cynaroside	23.70	12.1/16.0	0.0366	11.06 ± 0.41
	Cosmosiin	28.20	6.3/9.2	0.0083	05.42 ± 0.05
	Luteolin	36.70	2.6/4.1	0.0313	00.90 ± 0.03
	Chrysin	40.50	1.5/2.8	0.0323	00.004 ± 0.00
	Acacetin	40.70	1.5/2.5	0.036	00.81 ± 0.03
	Apigenin	38.20	1.3/2.0	0.0178	00.36 ± 0.01
Isoflavones	Genistein	36.90	3.7/5.3	0.0337	00.05 ± 0.00
Flavanones	Hesperidin	25.80	19.0/26.0	0.0335	03.93 ± 0.13
	Naringenin	35.90	2.6/3.9	0.0392	00.21 ± 0.01
	Hesperetin	36.70	2.6/3.9	0.0392	00.25 ± 0.01
	Amentoflavone	39.70	2.8/5.1	0.0340	00.003 ± 00.00
Flavonols	Rutin	25.60	15.7/22.7	0.0247	00.65 ± 0.02
	Isoquercitrin	25.60	8.7/13.5	0.0220	00.39 ± 0.090
	Astragalin	30.40	6.6/8.2	0.0114	00.07 ± 0.00
	Kaempferol	37.90	10.2/15.4	0.0212	00.06 ± 0.00
Phenolic aldehyde	Protocatechuic aldehydes	8.50	15.4/22.2	0.0396	00.16 ± 0.006

Note: Results are expressed as mean values of triplicate samples followed by the corresponding standard deviations (±SD), with a number of replicates n = 03; LOD/LOQ (μg/L)^f, limit of detection/quantification; U^g (%), percentage relative uncertainty to 95% confidence level (k = 2).

Abbreviations: RT, retention time; SD, standard deviations.